- 1556 Philip begins his reign as King of Spain
- 1566 Beeldenstorm in the Netherlands
- 1566 James Stuart of Scotland born
- 1567 Kirk O’ Field murder of Henry, Lord Darnley
- 1567 Duke of Alba appointed Military Governor of Netherlands
- 1568 Egmont and Hoorne executed in Brussels
- 1568 Marie Stuart imprisoned in England
- 1570 Pope excommunicates Elizabeth I (Ridolphi Plot hatched)
- 1571 Battle of Lepanto
- 1572 Elizabeth expels the Watergeuzen, who seize the Brill
- 1576 Don John appointed Military Governor of the Netherlands
- 1576 Spanish Fury (sack of Antwerp)
- 1576 Pacification of Ghent
- 1579 Union of Utrecht and Union of Arras formed
- 1581 Act of Abjuration (Declaration of Dutch Independence)
- 1581 Philip becomes King of Portugal
- 1584 William of Orange is assassinated
- 1584-85 siege of Antwerp (River Scheldt closed to shipping until 1792!)
- 1585 Treaty of Nonsuch (Robert Dudley, Earl of Leicester becomes Military Governor of the United Provinces)
- 1587 Marie Stuart executed by Elizabeth I
- 1587-89 War of the Three Henrys (Valois, Navarre, Guise)
- 1588 The Spanish Armada sails against England
- 1589 Henri IV de Bourbon de Navarre becomes king of France
- 1590-98 War between France and Spain (Spanish troops occupy Paris)
- 1594 After converting to Catholicism, Henri IV crowned king in Paris
- 1596 Combined Anglo-Dutch fleet of over 140 ships seizes Cadiz (with 15,000 soldiers under the command of the Earl of Essex and Louis of Nassau)
- 1596 and 1597 two more Spanish armadas attempt to sail against England – and fail.
- 1598 – Henry IV issues the Edict of Nantes
- 1598 Peace of Vervins between France and Spain
- 1598 Philip II dies
- 1602 VOC established
- 1603 Queen Elizabeth I dies (Marie Stuart’s son takes English throne as James I)
- 1604 Treaty of London (England makes peace with Spain)
- 1609 Twelve Years’ Truce (name was given to the period later)
- 1610 Henri IV assassinated
- 1618 beginning of the Thirty Years War
- 1648 Peace of Westphalia (The Republic of the United Netherlands formally recognized by Spain)
Timeline – Anglo-Spanish War
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